Triptorelin acetate CAS: 140194-24-7

CAS NO: 140194-24-7
Chemical Name: Triptorelin acetate
CAS No.: 140194-24-7
Molecular Formula: C64H82N18O13.C2H4O2
Formula Weight: 1371.52
Synonyms: 6-D-Tryptophan Luteinizing Hormone-Releasing Factor (Swine) Acetat
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Description

Do you know what Triptorelin is? Today I'll explain. Triptorelin is an artificial hormone; of course, it is also a gonadotropin-releasing hormone (GnRH) agonist, which inhibits the expression of luteinising hormone (LH) and follicle-stimulating hormone (FSH), and is a potent inhibitor of the synthesis of testosterone and oestrogen, and is currently used to treat advanced prostate cancer, but the treatment time is relatively long, and it can take months or years, and it is one of the hormonal anti-tumour drugs. It is a hormonal anti-tumour agent, which can also be used to treat endometriosis and infertility.

Triptorelin is also used to treat central precocious puberty (CPP) in children over the age of two; this is a condition that causes children to reach puberty too early, resulting in faster than normal bone growth and development of sexual characteristics. Triptorelin is a medication that belongs to a class of gonadotropin-releasing hormone (GnRH) agonists. Triptorelin works by reducing the amount of certain hormones in the body.

 

As mentioned earlier, Triptorelin is a gonadotropin-releasing hormone (GnRH) blocker. Triptorelin blocks certain messages from the hypothalamus and stimulates the pituitary gland to produce luteinising hormone. Luteinising hormone causes the testes to produce testosterone. Therefore, blocking GnRH stops the testes from producing testosterone.

Testosterone is needed to support the growth of prostate cancer. Triptorelin may inhibit or slow the growth of prostate cancer. In women, Triptorelin stops the ovaries from producing oestrogen. Similarly, some breast cancers depend on oestrogen for growth. Therefore, lowering oestrogen levels can slow or stop the growth of cancer.

 

Triptorelin is used and dosed as follows: intramuscular injection (usually located in the buttocks), used as follows: 3.75 mg per intramuscular injection. The dose is increased by 3.75 mg every 4 weeks or every 12 weeks or every 24 weeks, respectively. During the first few weeks after injection, Triptorelin may cause hormone levels to rise. During this time, your doctor will closely monitor you for new or worsening symptoms.

 

Common side effects may include allergic reactions, joint pain, rash, fatigue, asthma, hot flushes, decreased libido, erectile dysfunction, breast tenderness or change in size, ovarian cysts, depression, nausea, diarrhoea, weight gain and fluid retention.

 

Triptorelin is contraindicated in women who are pregnant or may become pregnant. It is important to tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you find out that you are pregnant while you are using Triptorelin Injection, contact your doctor right away. Triptorelin Injection may cause damage to the foetus.

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